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The Cochrane database of systematic reviews.

If they have taken estrogen in the past and had a high increase of triglycerides (a kind of fat in the blood).

Comparisons of baseline characteristics between treatment groups were performed with the use of one-way analysis of variance for continuous variables and chi-square tests for categorical variables.

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Valium, tricyclic antidepressants, chemotherapy, and some medications prescribed to people who are HIV positive may cause gynecomastia in some people.

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This estimated risk would have made them eligible for the Breast Cancer Prevention Trial and the Study of Tamoxifen and Raloxifene (STAR).

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For instance, systolic blood pressure (SBP) increased at a steeper rate in women with each decade from 35 to 44 years (average SBP 113.

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Evista was compared to in the 5-year study, and wasn't found to be more effective in lowering the incidence of invasive breast cancer.

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Coronary and revascularization outcomes were assessed separately for women with CHD risk factors and those with established CHD through the use of Cox proportional-hazards models.

Ketamine, an anesthetic drug, may be helpful for patients with severe treatment-resistant or bipolar depression.

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The development of statistical methodologies for race-specific cancer risk assessment and the risk-benefit assessment of therapies associated with multiple endpoints of potential benefit and harm has evolved from this collaboration.

The effects observed for tamoxifen and raloxifene show persistence several years after active treatment is discontinued, with longer duration of effect noted for tamoxifen than for raloxifene.

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Two large, prospective, global Phase III trials of bazedoxifene for osteoporosis prevention and treatment have been completed.

Raloxifene and its glucuronide conjugates are interconverted by reversible systemic metabolism and enterohepatic cycling, thereby prolonging its plasma elimination half-life to 27.

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Menopause can also be caused by ovarian failure from cancer treatments, such as chemotherapy or radiation.

Raloxifene is a selective estrogen receptor modulator (SERM), which means that it affects some (but not all) of the same receptors as estrogen, and in some instances, it blocks or antagonizes estrogen.

The expression of the essential NAD(P)H oxidase subunits p22phox and nox1, however, is not altered by raloxifene.

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NEW YORK (Reuters Health) - Doctors should talk about breast cancer-reducing drugs with women and offer tamoxifen or raloxifene to those that have a high risk of cancer and aren't likely to suffer side effects, a government-backed panel said on Monday.

MONDAY, Oct. 11, 2010 HealthDay News If you want to leave your dog home alone without having to worry about chewed furniture or neverending barking, youd better hope your dog knows how to look at the sunny side of life.

This means that out of 1000 women taking Tamoxifen, Arimidex, etc.

Those patients with tumors expressing high HER2 or AIB1 separately had a good disease-free survival ().

Breast cancer and post-menopausal hormone therapy.

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Other approaches short of stopping tamoxifen therapy include nutritional advice and weight loss, abstinence from alcohol, and possibly medical therapies for nonalcoholic steatohepatitis (which are currently investigational and have not been shown to be specifically helpful in tamoxifen induced fatty liver).

There were two serious adverse events (a pneumothorax and a seizure) that occurred during administration of raloxifene, which resulted in discontinuation from the study for each participant; however, in each case, the primary care treatment team determined that these serious adverse events were unlikely to have resulted from the administration of raloxifene.

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There may be other drugs used in these conditions that are not listed here.

Primary, age-related, or low-turnover osteoporosis results from decreasing bone mineral density and bone quality with age.

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Or, since results may vary, some MAY NOT die.

The researchers asked the women to assess the content of their dream on an emotional coloration scale that measured the tone of their dream.

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Problems focusing and learning - Some women may also have short-term memory problems, as well as finding it hard to concentrate on something for long.

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Incidence of Invasive Breast Cancer in Postmenopausal Women After Discontinuation of Long-Term Raloxifene Administration.

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Adverse events of uterine cancer, venous thrombolic events, and cataracts were more common in tamoxifen-treated women, and there was no difference in ischemic heart disease events, strokes, or fractures.

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Those women with abnormalities on endometrial biopsy performed because of abnormal vaginal bleeding may consider stopping tamoxifen in consultation with their gynecologist or primary care physician.

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SERMs: Meeting the Promise of Multifunctional Medicines.

Toremifene Citrate is an oral selective estrogen receptor modulator (SERM), used in the treatment of advanced breast cancer.

Quite often generic drugs are manufactured by the same company that makes their brand-name counterparts.

Like other products containing estrogen, it should be used for the shortest duration consistent with treatment goals and risks for the individual woman.

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Chiropractic intervention in the treatment of postmenopausal climacteric symptoms and insomnia: A review.

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She had no history of liver disease, denied alcohol use and had no risk factors for viral hepatitis.

Effects of Bazedoxifene on BMD and Bone Turnover in Postmenopausal Women: 2-Yr Results of a Randomized, Double-Blind, Placebo-, and Active-Controlled Study.

If they have liver or kidney disease.

Raloxifene is a SERM that has been approved by the FDA to treat osteoporosis; it inhibits bone resorption, increases spine BMD slightly, and decreases the risk of vertebral fractures by 30% but has no effect on nonvertebral or hip fractures.

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Several tests can measure bone density, and they are all painless, noninvasive, and safe.

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These findings seem to be supported by results of the recently published European trial, in which raloxifene decreased bone turnover markers to levels similar to those found in premenopausal women.

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He has listed on his health history that he is taking a nitrate for angina.

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Pharmacists say patients switching to other generic brands is possible but could cause new risks for people.

Compared with other therapies for osteoporosis, raloxifene has a smaller impact on bone mineral density, a similar effect on the occurrence of fractures, and no effect on the frequency of non-vertebral fractures.

In a clinical trial of postmenopausal women with documented coronary heart disease or at increased risk for coronary events, an increased risk of death due to stroke was observed after treatment with EVISTA.

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However, 5 years of adjuvant tamoxifen has been shown to reduce the relative risk of recurrence by 54% in women with ER-positive disease and, in the absence of contraindications, all patients with ER-positive tumors diagnosed prior to age 40 require either chemotherapy and endocrine therapy or endocrine therapy alone.

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There is variability in women's responses to menopause.

Bone turnover marker differences when raloxifene or alendronate are added to PTH could be a result of either differences in the effect of these agents on bone biology or because of differences in the relative potency of these antiresorptive agents.

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Tamoxifen, the generic name of Nolvadex, is the oldest and most-prescribed SERM.

When the treatment groups were compared by baseline categories of age, history of lobular carcinoma in situ (LCIS), history of atypical hyperplasia, Gail model-derived 5-year predicted risk of breast cancer and the number of relatives with a history of breast cancer, the pattern of no differential effect by treatment assignment was consistent, and none of the RRs in these subsets were statistically significant.

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The women were randomly assigned to receive either 60 mg or 120 mg orally of raloxifene per day, or oral placebo.

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As breast and ovarian cancers require estrogen to grow, AIs are taken to either block the production of estrogen or block the action of estrogen on receptors.

The incidences of stroke, heart disease, and bone fracture are similar to those in women treated with tamoxifen.

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Glaser thinks this will likely remain the status quo for a while, given the prohibitive cost of conducting the long-term safety studies needed to win fuller FDA approval.

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You also should not use Evista if you are allergic to raloxifene, if you are pregnant or breast-feeding.

These findings suggest that the atrophy of the lean body mass and its component organs and the enlargement of the mass of adipose tissue that are characteristic of the elderly result at least in part from diminished secretion of growth hormone.

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